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Description

Patients were randomly assigned in a 2:1 ratio to receive cabozantinib (140 mg per day) or placebo

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Unlike traditional weight loss medications that target a single hormonal pathway, tirzepatide's dual-action mechanism stimulates both GLP-1 and GIP receptors

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SIRT2 regulates tumour hypoxia response by promoting HIF-1alpha hydroxylation

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Blackburn K, Green D

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